Biochemist Jennifer Doudna won the 2020 Nobel Prize in Chemistry for pioneering CRISPR, a revolutionary biotech tool that can edit DNA with unprecedented precision and ease. But how exactly does CRISPR work, and what consequences may arise from altering our internal makeup? She talks to Chris about the remarkable effects CRISPR can have on our lives--from eradicating genetic diseases to slowing the climate crisis--as well as the ethical and moral questions we must grapple with when it comes to changing who we are.