The brain is an amazing and complex organ. And while many people are fascinated by the brain, they can't really tell you that much about the properties about how the brain works because we don't teach neuroscience in schools.
Mozak je čudesan i složen organ. Iako mozak fascinira mnoge ljude, ne znaju mnogo o tome kako zapravo mozak funkcionira jer nas ne podučavaju neuroznanosti u školi.
And one of the reasons why is that the equipment is so complex and so expensive that it's really only done at major universities and large institutions. And so in order to be able to access the brain, you really need to dedicate your life and spend six and a half years as a graduate student just to become a neuroscientist to get access to these tools.
Jedan od razloga zašto je oprema toliko složena i skupa jest što se koristi samo na velikim sveučilištima i velikim institucijama. Kako bismo mogli doći do mozga, moramo tome posvetiti svoj život i proći šest i pol godina diplomskog studija da postanemo neuroznanstvenici i dobijemo pristup tim alatima.
And that's a shame because one out of five of us, that's 20 percent of the entire world, will have a neurological disorder. And there are zero cures for these diseases. And so it seems that what we should be doing is reaching back earlier in the eduction process and teaching students about neuroscience so that in the future, they may be thinking about possibly becoming a brain scientist.
To je prava šteta s obzirom na to da će svaka peta osoba ovdje, to je 20 posto cijelog svijeta, patiti od nekog neurološkog poremećaja. Nema lijeka za te bolesti. Stoga bismo trebali u ranijem procesu obrazovanja podučavati učenike o neuroznanosti kako bi se oni u budućnosti možda opredijelili za karijeru neuroznanstvenika.
When I was a graduate student, my lab mate Tim Marzullo and myself, decided that what if we took this complex equipment that we have for studying the brain and made it simple enough and affordable enough that anyone that you know, an amateur or a high school student, could learn and actually participate in the discovery of neuroscience.
Na diplomskom studiju ja i moj laboratorijski partner Tim Marzullo, odlučili smo da tu složenu opremu za proučavanje mozga pojednostavimo i učinimo dovoljno povoljnom tako da svatko, laik ili srednjoškolac, može učiti i zaista sudjelovati u otkriću neuroznanosti.
And so we did just that. A few years ago, we started a company called Backyard Brains and we make DIY neuroscience equipment and I brought some here tonight, and I want to do some demonstrations. You guys want to see some?
Upravo to smo i napravili. Prije nekoliko godina, pokrenuli smo tvrtku Backyard Brains. Radimo neuroznanstvenu opremu po principu "uradi sam". Nešto od toga sam i donio. Htio bih vam demonstrirati nešto. Želite li vidjeti nešto?
So I need a volunteer. So right before -- what is your name? (Applause) Sam Kelly: Sam. Greg Gage: All right, Sam, I'm going to record from your brain. Have you had this before? SK: No. GG: I need you to stick out your arm for science, roll up your sleeve a bit, So what I'm going to do, I'm putting electrodes on your arm, and you're probably wondering, I just said I'm going to record from your brain, what am I doing with your arm?
Trebam dobrovoljca. Točno prije -- kako se zovete? (Pljesak) Sam Kelly: Sam. Greg Gage: U redu, Sam. Snimit ću vam mozak. Jeste li ikada ovo radili? SK: Ne. GG: Ispružite ruku za znanost, podignite malo rukav. Postavljam vam elektrode na ruku. Vjerojatno se pitate, što radim s vašom rukom, s obzirom da sam upravo rekao da ću snimati vaš mozak.
Well, you have about 80 billion neurons inside your brain right now. They're sending electrical messages back and forth, and chemical messages. But some of your neurons right here in your motor cortex are going to send messages down when you move your arm like this. They're going to go down across your corpus callosum, down onto your spinal cord to your lower motor neuron out to your muscles here, and that electrical discharge is going to be picked up by these electrodes right here and we're going to be able to listen to exactly what your brain is going to be doing. So I'm going to turn this on for a second.
Imate oko 80 milijardi neurona u mozgu. Oni na sve strane šalju električne i kemijske poruke. No neki vaši neuroni ovdje u motoričkoj moždanoj kori odaslat će poruke dolje kada ovako pokrenete ruku. One će sići preko žuljevitog tijela, i spustiti se leđnom moždinom, do vaših donjih motoričkih neurona u ovaj mišić. Taj će živčani impuls zabilježiti ove elektrode i moći ćemo čuti što točno vaš mozak radi. Uključit ću nakratko ovo.
Have you ever heard what your brain sounds like? SK: No. GG: Let's try it out. So go ahead and squeeze your hand. (Rumbling) So what you're listening to, so this is your motor units happening right here. Let's take a look at it as well. So I'm going to stand over here, and I'm going to open up our app here. So now I want you to squeeze. (Rumbling)
Jeste li ikada čuli zvuk svoga mozga? SK: Ne. GG: Idemo to probati. Stisnite ruku. (Tutnjanje) Ovo što slušate, ovo se upravo manifestiraju vaše motoričke jedinice. Pogledajmo i kako to izgleda. Stat ću ovdje, i otvorit ću našu aplikaciju. Sada stisnite ruku. (Tutnjanje)
So right here, these are the motor units that are happening from her spinal cord out to her muscle right here, and as she's doing it, you're seeing the electrical activity that's happening here. You can even click here and try to see one of them. So keep doing it really hard. So now we've paused on one motor action potential that's happening right now inside of your brain.
Točno ovdje, ovo su motoričke jedinice koje se manifestiraju od njene leđne moždine sve do ovog njenog mišića. Dok to ona radi, vidite električne impulse koji ovdje putuju. Možete čak i kliknuti ovdje i vidjeti jednoga od njih. Nastavite to raditi snažno. Sada smo se zaustavili na jednom potencijalu motoričke radnje koja se upravo sada odvija u vašem mozgu.
Do you guys want to see some more? (Applause) That's interesting, but let's get it better. I need one more volunteer. What is your name, sir? Miguel Goncalves: Miguel. GG: Miguel, all right. You're going to stand right here. So when you're moving your arm like this, your brain is sending a signal down to your muscles right here. I want you to move your arm as well. So your brain is going to send a signal down to your muscles. And so it turns out that there is a nerve that's right here that runs up here that innervates these three fingers, and it's close enough to the skin that we might be able to stimulate that so that what we can do is copy your brain signals going out to your hand and inject it into your hand, so that your hand will move when your brain tells your hand to move. So in a sense, she will take away your free will and you will no longer have any control over this hand. You with me?
Želite li vidjeti još više? (Pljesak) Ovo je zanimljivo, no pokušajmo to učiniti zanimljivijim. Trebam još jednog dobrovoljca. Kako se zovete? Miguel Goncalves: Miguel. GG: Miguel, uredu. Stajat ćete ovdje. Kada pomičete rukom ovako, vaš mozak šalje signal ovim dolje mišićima. Htio bih da i vi pomičete ruku. Mozak će vam odaslati signal mišićima. Ispostavilo se da točno ovdje postoji živac koji seže sve do gore i oživčuje ova tri prsta, a dovoljno je blizu koži da ga možemo stimulirati. Na taj način možemo kopirati vaše moždane signale koji putuju u vašu ruku i unijeti ih u vašu ruku, pa će se vaša ruka pomicati onda kada vaš mozak naloži vašoj ruci da se miče. To znači da će ona oduzeti vašu slobodu odlučivanja i nećete više imati kontrolu nad ovom rukom. Jeste spremni?
So I just need to hook you up. (Laughter) So I'm going to find your ulnar nerve, which is probably right around here. You don't know what you're signing up for when you come up. So now I'm going to move away and we're going to plug it in to our human-to-human interface over here.
Moram vas samo priključiti. (Smijeh) Moram pronaći vaš ulnarni živac, koji je vjerojatno ovdje negdje. Ne znate u što ste se upustili kada dođete na pozornicu. Odmaknut ću se i uključiti vas na naše međuljudsko sučelje.
Okay, so Sam, I want you to squeeze your hand again. Do it again. Perfect. So now I'm going to hook you up over here so that you get the -- It's going to feel a little bit weird at first, this is going to feel like a -- (Laughter) You know, when you lose your free will, and someone else becomes your agent, it does feel a bit strange.
Sam, stisnite ponovo svoju ruku. Ponovo. Odlično. Sada ću vas spojiti ovdje. Isprva ćete se osjećati malo čudno, ovo će se činiti kao -- (Smijeh) Kada izgubite slobodnu volju i netko drugi postane vaš izvršitelj, to je zaista neobičan osjećaj.
Now I want you to relax your hand. Sam, you're with me? So you're going to squeeze. I'm not going to turn it on yet, so go ahead and give it a squeeze.
Sada opustite ruku. Sam, jeste li spremni? Stisnut ćete ruku. Još neću uključiti program, pa samo stisnite.
So now, are you ready, Miguel? MG: Ready as I'll ever be. GG: I've turned it on, so go ahead and turn your hand. Do you feel that a little bit? MG: Nope. GG: Okay, do it again? MG: A little bit. GG: A little bit? (Laughter) So relax. So hit it again. (Laughter) Oh, perfect, perfect. So relax, do it again.
Jeste li spremni, Miguel? MG: Spremniji od ovog ne mogu biti. GG: Uključio sam ga, slobodno okrenite ruku. Osjećate li to malo? MG: Ne. GG: Uredu. Ponovite. MG: Malo. GG: Malo? (Smijeh) Opustite se. Stisnite ponovo. (Smijeh) Savršeno! Opustite, stisnite ponovo.
All right, so right now, your brain is controlling your arm and it's also controlling his arm, so go ahead and just do it one more time. All right, so it's perfect. (Laughter)
Uredu, sada upravo Vaš mozak kontrolira vašu ruku, a ujedno kontrolira i njegovu ruku. Slobodno ponovite. Savršeno. (Smijeh)
So now, what would happen if I took over my control of your hand? And so, just relax your hand. What happens? Ah, nothing. Why not? Because the brain has to do it. So you do it again. All right, that's perfect.
Što bi se dogodilo da ja preuzmem kontrolu nad vašom rukom? Opustite ruku. Što se događa? Ništa. Zašto? Zato što je mozak taj koji mora kontrolirati. Ponovite. Odlično.
Thank you guys for being such a good sport. This is what's happening all across the world -- electrophysiology! We're going to bring on the neuro-revolution.
Hvala vam oboje na hrabrosti. Ovo se događa diljem svijeta elektrofiziologija! Donijet ćemo neuro-revoluciju.
Thank you.
Hvala vam.
(Applause)
(Pljesak)