One way to change our genes is to make new ones, as Craig Venter has so elegantly shown. Another is to change our lifestyles. And what we're learning is how powerful and dynamic these changes can be, that you don't have to wait very long to see the benefits. When you eat healthier, manage stress, exercise and love more, your brain actually gets more blood flow and more oxygen. But more than that, your brain gets measurably bigger. Things that were thought impossible just a few years ago can actually be measured now. This was figured out by Robin Williams a few years before the rest of us.
Jedan način da promijenimo svoje gene jest da napravimo nove, kao što je to elegantno pokazao Craig Venter. Drugi način je da promijenimo životni stil. Upravo učimo koliko su te promjene snažne i dinamične, i kako ne trebate dugo čekati na rezultate. Kada zdravije jedete, kontrolirate stres, vježbate i volite više, vaš mozak dobiva više krvi i kisika. Još važnije jest da vaš mozak tada ustvari raste. Stvari koje su prije par godina smatrane nemogućim danas se mogu izmjeriti. To je shvatio Robin Williams par godina prije nas ostalih.
Now, there's some things that you can do to make your brain grow new brain cells. Some of my favorite things, like chocolate and tea, blueberries, alcohol in moderation, stress management and cannabinoids found in marijuana. I'm just the messenger. (Laughter) What were we just talking about? (Laughter) And other things that can make it worse, that can cause you to lose brain cells. The usual suspects, like saturated fat and sugar, nicotine, opiates, cocaine, too much alcohol and chronic stress.
Ovo su stvari koje možete napraviti kako bi vaš mozak proizvodio nove moždane stanice. Neke od meni najdražih su čokolada i čaj, borovnice, alkohol u umjerenim količinama, kontroliranje stresa i opioidi koji se mogu naći u marihuani. Ja sam samo glasnik. (Smijeh) O čemu smo ono upravo pričali? (Smijeh) A ove stvari mogu sve pogoršati i uzrokovati gubitak moždanih stanica. Uobičajeni krivci, poput zasićenih masti i šećera, nikotina, opijata, kokaina, previše alkohola i kroničnog stresa.
Your skin gets more blood flow when you change your lifestyle, so you age less quickly. Your skin doesn't wrinkle as much. Your heart gets more blood flow. We've shown that you can actually reverse heart disease. That these clogged arteries that you see on the upper left, after only a year become measurably less clogged. And the cardiac PET scan shown on the lower left, the blue means no blood flow. A year later -- orange and white is maximum blood flow. We've shown you may be able to stop and reverse the progression of early prostate cancer and, by extension, breast cancer, simply by making these changes. We've found that tumor growth in vitro was inhibited 70 percent in the group that made these changes, whereas only nine percent in the comparison group.
Vaša koža je bolje prokrvljena kada promijenite životni stil i zato sporije starite i imate manje bora. Kroz vaše srce prolazi više krvi. Dokazali smo da možete izliječiti srčane bolesti. Ove začepljene arterije gore lijevo su nakon samo jedne godine mnogo manje začepljene. Na PET scan-u dolje lijevo plava boja označava slab protok krvi. Nakon godinu dana narančasta i bijela boja pokazuju snažan protok. Vi ste u mogućnosti zaustaviti i poništiti tijek ranog raka prostate, kao i raka dojke ako unesete ove promjene u svoj život. Rast tumora in vitro zaustavljen je u 70 posto ispitanika koji su promijenili svoje navike, i u samo devet posto onih koji to nisu učinili.
These differences were highly significant. Even your sexual organs get more blood flow, so you increase sexual potency. One of the most effective anti-smoking ads was done by the Department of Health Services, showing that nicotine, which constricts your arteries, can cause a heart attack or a stroke, but it also causes impotence. Half of guys who smoke are impotent. How sexy is that?
Ove su razlike veoma značajne. Čak i vaši spolni organi dobivaju više krvi čime se povećava vaša spolna moć. Najučinkovitiju reklamu protiv pušenja napravilo je ministarstvo zdravstva koje je pokazalo da nikotin sužava vaše arterije i može uzrokovati srčani i moždani udar, ali isto može dovesti i do impotencije. Polovica muškaraca pušača pati od impotencije. Seksi, zar ne?
Now we're also about to publish a study -- the first study showing you can change gene expression in men with prostate cancer. This is what's called a heat map -- and the different colors -- and along the side, on the right, are different genes. And we found that over 500 genes were favorably changed -- in effect, turning on the good genes, the disease-preventing genes, turning off the disease-promoting genes.
Uskoro ćemo objaviti istraživanje koje pokazuje da je moguća promjena gena u oboljelih od raka prostate. Ovo je toplinska karta, s različitim bojama. Geni su s desne strane. 500 gena se promijenilo nabolje i aktiviralo "dobre" gene koji sprječavaju bolesti te poništilo one gene koji uzrokuju bolesti.
And so these findings I think are really very powerful, giving many people new hope and new choices. And companies like Navigenics and DNA Direct and 23andMe, that are giving you your genetic profiles, are giving some people a sense of, "Gosh, well, what can I do about it?" Well, our genes are not our fate, and if we make these changes -- they're a predisposition -- but if we make bigger changes than we might have made otherwise, we can actually change how our genes are expressed. Thank you. (Applause)
Ove spoznaje su veoma snažne jer mnogim ljudima pružaju novu nadu i izbor. Tvrtke kao Navigenix, DNA Direct i 23andME koje izrađuju vaše genske profile kod ljudi izazivaju pitanje: "Što ja sad tu mogu napraviti?" Naši geni ne određuju našu sudbinu. Oni jesu predispozicija za bolesti, ali ako napravimo promjene koje inače ne bismo, možemo promijeniti način na koji naši geni rade. Hvala vam. (Pljesak)