Modern psychiatric drugs treat the chemistry of the whole brain, but neurobiologist David Anderson has a more nuanced view of how the brain functions. He shares new research that could lead to targeted psychiatric medications -- that work better and avoid side effects. How's he doing it? For a start, by making a bunch of fruit flies angry.

After a billion years of evolution, fungi are masters of invention and resilience. What wisdom can we draw from their long, remarkable existence? Mycologist David Andrew Quist explores how fungi's innate biointelligence, penchant for collaboration and incredible regeneration abilities can show us new ways to think about complex problems -- and m...

Did you know that gold is extraterrestrial? Instead of arising from our planet's rocky crust, it was actually cooked up in space and is present on Earth because of cataclysmic stellar explosions called supernovae. CERN Scientist David Lunney outlines the incredible journey of gold from space to Earth. [Directed by Andrew Foerster, narrated by Ad...

David Thouless, Duncan Haldane, and Michael Kosterlitz won the Nobel Prize in Physics in 2016 for discovering that even microscopic matter at the smallest scale can exhibit macroscopic properties and phases that are topological. But ... what does that mean? Fan Zhang helps decode some seriously tricky science. [Directed by Anton Trofimov, narrat...

Every day, we are bombarded by attention grabbing headlines that promise miracle cures to all of our ailments -- often backed up by a "scientific study." But what are these studies, and how do we know if they are reliable? David H. Schwartz dissects two types of studies that scientists use, illuminating why you should always approach the claims ...

The modern hard drive is an object that can likely hold more information than your local library. But how does it store so much information in such a small space? Kanawat Senanan details the generations of engineers, material scientists, and quantum physicists who influenced the creation of this incredibly powerful and precise tool. [Directed by...

Agriculture fundamentally changed the way humans live — but at a cost, using up huge tracts of land and wreaking havoc on the environment, even as millions still go hungry. Entrepreneur and investor David Friedberg paints a picture of the evolution of agriculture and introduces a scientific breakthrough — "boosted breeding" — that might just tra...

Imagine aliens land on Earth a million years from now. What will these curious searchers find of us? They will find what geologists, scientists, and other experts are increasingly calling the Anthropocene, or new age of mankind. David Biello explains how the impacts that humans have made have become so pervasive, profound, and permanent that som...

How good are you with money? What about reading people's emotions? How healthy are you, compared to other people you know? Knowing how our skills stack up against others is useful in many ways. But psychological research suggests that we're not very good at evaluating ourselves accurately. In fact, we frequently overestimate our own abilities. D...

In 1815, Mount Tambora erupted and its emissions spread across the globe, blotting out the sun for almost an entire year. This wreaked havoc on agriculture, leading to famines all across the Northern hemisphere. It was the year without summer— one of the darkest periods in human history. So why are some modern researchers considering repeating i...

Whales frequently surface to take in air and let out massive plumes of waste. And while this slurry might seem disgusting, whale poop is much more desirable than it may seem. In fact, it may be one of the most important substances in the ocean — and the world. So, what makes whale poop so vital to our ecosystems? David Biello shares the surprisi...

The Infinite Hotel, a thought experiment created by German mathematician David Hilbert, is a hotel with an infinite number of rooms. Easy to comprehend, right? Wrong. What if it's completely booked but one person wants to check in? What about 40? Or an infinitely full bus of people? Jeff Dekofsky solves these heady lodging issues using Hilbert's...

About once every century, a massive star somewhere in our galaxy runs out of fuel. No longer able to produce sufficient energy to maintain its structure, it collapses under its own gravitational pressure and explodes in a supernova. The death of that star is the birth of a neutron star: one of the densest known objects in the universe. David Lun...

Soon after whaling ships began operating in the North Pacific, an interesting trend emerged. Within just a few years, whalers saw a 58% drop in their successful strikes. Sperm whales had suddenly become harder to kill— they had begun fleeing the boats instead of forming their usual defensive circles. Were whales communicating new strategies to e...

"Life's beauty is inseparable from its fragility," says psychologist Susan David. In a special virtual conversation, she shares wisdom on how to build resilience, courage and joy in the midst of the coronavirus pandemic. Responding to listeners' questions from across the globe, she offers ways to talk to your children about their emotions, keep ...

It can be easy to believe that humans are insignificant. We're specks of dust on a random planet in a vast universe. Less powerful than elephants. Fewer than ants. But David Deutsch believes that's all beside the point, because humans possess one unique skill: attaining knowledge. David Deutsch -- Oxford professor, father of quantum computing, r...

Since the widespread use of antibiotics began in the 1940s, we've tried to develop new drugs faster than bacteria can evolve -- but this strategy isn't working. Drug-resistant bacteria known as superbugs killed nearly 700,000 people last year, and by 2050 that number could be 10 million -- more than cancer kills each year. Can physics help? In a...

Since their emergence over 200,000 years ago, modern humans have established communities all over the planet. But they didn't do it alone. Whatever corner of the globe you find humans in today, you're likely to find another species as well: dogs. So how did one of our oldest rivals, the wolf, evolve into man's best friend? David Ian Howe traces ...

In 1961, an Antarctic expedition took a harrowing turn: Dr. Leonid Rogozov began feeling feverish, with an excruciating pain in his right side. It soon became clear that he had appendicitis. While Rogozov’s predicament was extreme, appendicitis is not uncommon; affecting roughly one in 12 people. So, what causes appendicitis? And why is this org...

Imagine you're watching a runaway trolley barreling down the tracks, straight towards five workers. You happen to be standing next to a switch that will divert the trolley onto a second track. Here's the problem: that track has a worker on it, too — but just one. What do you do? Do you sacrifice one person to save five? Eleanor Nelsen details th...

In 1901, David Hänig published research that led to what we know today as the taste map: an illustration that divides the tongue into four separate areas. It has since been published in textbooks and newspapers. There is just one problem: the map is wrong. So how do misconceptions like this spread, and what makes a fake fact so easy to believe? ...

In 1830, David Walker sewed a pamphlet into the lining of a coat. The volume was thin enough to be hidden, but its content was far from insubstantial. At the time, many members of the US government considered this pamphlet to be one of the most dangerous documents in American history. But what was this incendiary document? And who exactly was th...

The coronavirus pandemic won't be the last crisis to test public health systems worldwide, says physician and health policy leader Georges C. Benjamin. He details what's needed to lead us out of the pandemic and prevent future ones -- including a robust governmental health entity equipped with updated technology and well-trained staff -- and exp...

How can we return to work without spurring a second surge of coronavirus infection? Biologist Uri Alon shares a thought-provoking strategy: four days at work followed by 10 days of lockdown, a cycle that would exploit a weakness in the virus's biology and potentially cut its reproductive rate to a manageable level. Learn more about this approach...

New York Times pundit David Brooks describes a plan to rebuild broken communities and offers actionable steps to live a more meaningful life. (Audio only)

New York Times columnist David Pogue takes aim at technology’s worst interface-design offenders, and provides encouraging examples of products that get it right. To funny things up, he bursts into song.

David Hanson's robot faces look and act like yours: They recognize and respond to emotion, and make expressions of their own. Here, an "emotional" live demo of the Einstein robot offers a peek at a future where robots truly mimic humans.

David Binder is a major Broadway producer, but last summer he found himself in a small Australian neighborhood, watching locals dance and perform on their lawns -- and loving it. He shows us the new face of arts festivals, which break the boundary between audience and performer and help cities express themselves.

One hundred green-eyed logicians have been imprisoned on an island by a mad dictator. Their only hope for freedom lies in the answer to one famously difficult logic puzzle. Can you solve it? Alex Gendler walks us through this green-eyed riddle. [Directed by Artrake Studio, narrated by Addison Anderson].

Game designer David Perry says tomorrow's videogames will be more than mere fun to the next generation of gamers. They'll be lush, complex, emotional experiences -- more involving and meaningful to some than real life. With an excerpt from Michael Highland's film "As Real as Your Life."